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| Cat.No | ACP14623 | Target Name | CNTROB |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N137 |
|---|
Uniprot Id
Q8N137
Target Species
Human
Target Name
CNTROB
Target Full Name
Centrobin
Target Function
Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Centriole-associated, asymmetrically localizes to the daughter centriole.
Target Tissue Specificity
Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.
Target Synonyms
9830165K03Rik; Centrobin; centrobin; centrosomal BRCA2 interacting protein; Centrosomal BRCA2 interacting protein; Centrosomal BRCA2-interacting protein; CNTRB_HUMAN; Cntrob; LIP8; LYST interacting protein 8; LYST-interacting protein 8; LYST-interacting protein LIP8; PP1221; RGD1307488; RP23 26L6.9
Target Background
This gene encodes a centrosomal protein that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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