Home Products Proteins Recombinant Proteins Recombinant Human Ceramide synthase 6 (CERS6), Truncated

Recombinant Human Ceramide synthase 6 (CERS6), Truncated

ACP08202

Number

Order Exclusive Products Now

Request a Quote

High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP08202	Target Name	CERS6
Target Synonyms	CERS6; LASS6; Ceramide synthase 6; CerS6; LAG1 longevity assurance homolog 6; Sphingoid base N-palmitoyltransferase CERS6	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6ZMG9

Background Information

Uniprot Id

Q6ZMG9
Target Species

Human
Target Name

CERS6
Target Full Name

Ceramide synthase 6
Target Function

Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA; C16:0-CoA). Can use other acyl donors, but with less efficiency. N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. Ceramides generated by CERS6 play a role in inflammatory response. Acts as a regulator of metabolism and hepatic lipid accumulation. Under high fat diet, palmitoyl- (C16:0-) ceramides generated by CERS6 specifically bind the mitochondrial fission factor MFF, thereby promoting mitochondrial fragmentation and contributing to the development of obesity.
Target Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Synonyms

CERS6; LASS6; Ceramide synthase 6; CerS6; LAG1 longevity assurance homolog 6; Sphingoid base N-palmitoyltransferase CERS6

Inquire Recombinant Human Ceramide synthase 6 (CERS6), Truncated Now

Full Name *

Business Email Address *

Phone

Products/Services

Catalog Number

Quantity (μg, mg, g, μl, ml, L, kit)

Address

Project Description

AbTriva respects your privacy and protects your personal data in accordance with AbTriva. For more information, please see our data protection statement. *

Submit

Recombinant Human Ceramide synthase 6 (CERS6), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Ceramide synthase 6 (CERS6), Truncated Now

Related Products