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Recombinant Human Class A basic helix-loop-helix protein 15 (BHLHA15)

ACP16035

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16035 Target NameBHLHA15
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-189Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ7RTS1
Background Information
  • Uniprot Id

    Q7RTS1

  • Target Species

    Human

  • Target Name

    BHLHA15

  • Target Full Name

    Class A basic helix-loop-helix protein 15

  • Target Function

    Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Expressed in brain, liver, spleen and skeletal muscle.

  • Target Synonyms

    Basic helix loop helix domain containing class B 8; Basic helix loop helix family member a15; BHA15_HUMAN; Bhlha15; bHLHB8; Class A basic helix-loop-helix protein 15; Class B basic helix-loop-helix protein 8; Class II bHLH protein MIST1; intestine and stomach expression 1; MIST 1; MIST-1; MIST1; Muscle; Muscle intestine and stomach expression 1; protein MIST1

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