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| Cat.No | ACP16035 | Target Name | BHLHA15 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-189 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7RTS1 |
|---|
Uniprot Id
Q7RTS1
Target Species
Human
Target Name
BHLHA15
Target Full Name
Class A basic helix-loop-helix protein 15
Target Function
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in brain, liver, spleen and skeletal muscle.
Target Synonyms
Basic helix loop helix domain containing class B 8; Basic helix loop helix family member a15; BHA15_HUMAN; Bhlha15; bHLHB8; Class A basic helix-loop-helix protein 15; Class B basic helix-loop-helix protein 8; Class II bHLH protein MIST1; intestine and stomach expression 1; MIST 1; MIST-1; MIST1; Muscle; Muscle intestine and stomach expression 1; protein MIST1
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