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| Cat.No | ACP10070 | Target Name | STAG3 |
|---|---|---|---|
| Target Synonyms | STAG3; Cohesin subunit SA-3; SCC3 homolog 3; Stromal antigen 3; Stromalin-3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UJ98 |
|---|
Uniprot Id
Q9UJ98
Target Species
Human
Target Name
STAG3
Target Full Name
Cohesin subunit SA-3
Target Function
Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Target Involvement
Premature ovarian failure 8 (POF8)
Target Subcellular Location
Nucleus. Chromosome. Chromosome, centromere.
Target Protein Families
SCC3 family
Target Tissue Specificity
Testis specific.
Target Synonyms
STAG3; Cohesin subunit SA-3; SCC3 homolog 3; Stromal antigen 3; Stromalin-3
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