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| Cat.No | ACP10204 | Target Name | CC2D2A |
|---|---|---|---|
| Target Synonyms | C2D2A_HUMAN; CC2D2A; Coiled coil and C2 domain containing 2A; Coiled-coil and C2 domain-containing protein 2A; JBTS9; KIAA1345; MKS6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P2K1 |
|---|
Uniprot Id
Q9P2K1
Target Species
Human
Target Name
CC2D2A
Target Full Name
Coiled-coil and C2 domain-containing protein 2A
Target Function
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
Target Involvement
Meckel syndrome 6 (MKS6); Joubert syndrome 9 (JBTS9); COACH syndrome (COACHS)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body.
Target Tissue Specificity
Strongly expressed in prostate, pancreas, kidney, lung, liver, retina, kidney, fetal brain and fetal kidney. Lower expression in spleen, small intestine, colon, skeletal muscle, ovary, thymus and heart.
Target Synonyms
C2D2A_HUMAN; CC2D2A; Coiled coil and C2 domain containing 2A; Coiled-coil and C2 domain-containing protein 2A; JBTS9; KIAA1345; MKS6
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