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| Cat.No | ACP12607 | Target Name | VPS50 |
|---|---|---|---|
| Target Synonyms | VPS50; CCDC132; KIAA1861; Syndetin; Coiled-coil domain-containing protein 132; EARP/GARPII complex subunit VPS50 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96JG6 |
|---|
Uniprot Id
Q96JG6
Target Species
Human
Target Name
VPS50
Target Full Name
Syndetin
Target Function
Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Target Subcellular Location
Recycling endosome. Membrane.
Target Protein Families
Syndetin family
Target Tissue Specificity
Ubiquitous, with higher expression in brain and skeletal muscle.
Target Synonyms
VPS50; CCDC132; KIAA1861; Syndetin; Coiled-coil domain-containing protein 132; EARP/GARPII complex subunit VPS50
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