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| Cat.No | ACP14664 | Target Name | DRC1 |
|---|---|---|---|
| Target Synonyms | DRC1; C2orf39; CCDC164Dynein regulatory complex protein 1; Coiled-coil domain-containing protein 164 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-740 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96MC2 |
|---|
Uniprot Id
Q96MC2
Target Species
Human
Target Name
DRC1
Target Full Name
Dynein regulatory complex protein 1
Target Function
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Target Involvement
Ciliary dyskinesia, primary, 21 (CILD21)
Target Subcellular Location
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Target Protein Families
DRC1 family
Target Synonyms
DRC1; C2orf39; CCDC164Dynein regulatory complex protein 1; Coiled-coil domain-containing protein 164
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