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| Cat.No | ACP03216 | Target Name | CCDC3 |
|---|---|---|---|
| Target Synonyms | CCDC3Coiled-coil domain-containing protein 3; Fat/vessel-derived secretory protein; Favine | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 22-270aa |
| Mol Weight | 32.1kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BQI4 |
|---|
Uniprot Id
Q9BQI4
Target Species
Human
Target Name
CCDC3
Target Full Name
Coiled-coil domain-containing protein 3
Target Function
Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs. Positively regulates lipid accumulation in adipose cells.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Expressed in umbilical vein endothelial cells (HUVEC), and at lower levels in aortic smooth muscle cells (HASMC).
Target Research Area
Others
Target Synonyms
CCDC3Coiled-coil domain-containing protein 3; Fat/vessel-derived secretory protein; Favine
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