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| Cat.No | ACP11015 | Target Name | CCDC8 |
|---|---|---|---|
| Target Synonyms | CCDC8; CCDC8_HUMAN; Coiled coil domain containing 8; Coiled-coil domain-containing protein 8; DKFZp564K0322; ENSMUSG00000041117; MGC72567 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-538 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H0W5 |
|---|
Uniprot Id
Q9H0W5
Target Species
Human
Target Name
CCDC8
Target Full Name
Coiled-coil domain-containing protein 8
Target Function
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Required for localization of CUL7 to the centrosome.
Target Involvement
3M syndrome 3 (3M3)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Target Tissue Specificity
Widely expressed with low levels in spleen, skeletal muscle, small intestine, kidney and liver.
Target Synonyms
CCDC8; CCDC8_HUMAN; Coiled coil domain containing 8; Coiled-coil domain-containing protein 8; DKFZp564K0322; ENSMUSG00000041117; MGC72567
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