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| Cat.No | ACP21783 | Target Name | COL6A5 |
|---|---|---|---|
| Target Synonyms | COL6A5; COL29A1; VWA4Collagen alpha-5(VI) chain; Collagen alpha-1(XXIX) chain; von Willebrand factor A domain-containing protein 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A8TX70 |
|---|
Uniprot Id
A8TX70
Target Species
Human
Target Name
COL6A5
Target Full Name
Collagen alpha-5(VI) chain
Target Function
Collagen VI acts as a cell-binding protein.
Target Involvement
Patients affected by atopic dermatitis display an abnormal distribution of COL29A1 mRNA and protein in skin suggesting that COL29A1 may be involved in the pathogenesis of the disease.
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Type VI collagen family
Target Tissue Specificity
Expressed in skin, followed by lung, small intestine, colon and testis. In skin, it is expressed in the epidermis with strongest staining in suprabasal viable layers. In ATOD patients, it is absent in the most differentiated upper spinous and granular lay
Target Synonyms
COL6A5; COL29A1; VWA4Collagen alpha-5(VI) chain; Collagen alpha-1(XXIX) chain; von Willebrand factor A domain-containing protein 4
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