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| Cat.No | ACP01434 | Target Name | C9 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 22-265aa | Mol Weight | 35.3 kDa |
| Protein Length | Partial | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P02748 |
|---|
Uniprot Id
P02748
Target Species
Human
Target Name
C9
Target Full Name
Complement component C9
Target Function
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
Target Involvement
Complement component 9 deficiency (C9D); Macular degeneration, age-related, 15 (ARMD15)
Target Subcellular Location
Secreted. Target cell membrane; Multi-pass membrane protein.
Target Protein Families
Complement C6/C7/C8/C9 family
Target Tissue Specificity
Plasma (at protein level).
Target Research Area
Immunology
Target Synonyms
C9; Complement component C9
Target Background
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.
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