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| Cat.No | ACP10966 | Target Name | COG4 |
|---|---|---|---|
| Target Synonyms | COG4Conserved oligomeric Golgi complex subunit 4; COG complex subunit 4; Component of oligomeric Golgi complex 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-785 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H9E3 |
|---|
Uniprot Id
Q9H9E3
Target Species
Human
Target Name
COG4
Target Full Name
Conserved oligomeric Golgi complex subunit 4
Target Function
Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1.
Target Involvement
Congenital disorder of glycosylation 2J (CDG2J)
Target Subcellular Location
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
COG4 family
Target Synonyms
COG4Conserved oligomeric Golgi complex subunit 4; COG complex subunit 4; Component of oligomeric Golgi complex 4
Target Background
The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.
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