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Recombinant Human Corticosteroid-binding globulin (SERPINA6)

ACP03876

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP03876 Target NameSERPINA6
FormLiquid or Lyophilized powderExpression SystemYeast
Expression Range23-405aaMol Weight44.6kDa
Protein LengthFull Length of Mature ProteinPurityGreater than 90% as determined by SDS-PAGE.
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP08185
Background Information
  • Uniprot Id

    P08185

  • Target Species

    Human

  • Target Name

    SERPINA6

  • Target Full Name

    Corticosteroid-binding globulin

  • Target Function

    Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.

  • Target Involvement

    Corticosteroid-binding globulin deficiency (CBG deficiency)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Serpin family

  • Target Tissue Specificity

    Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.

  • Target Research Area

    Transport

  • Target Synonyms

    CBG; CBG_HUMAN; corticosteroid binding globulin; Corticosteroid-binding globulin; serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6; Serpin A6; serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6; Serpina6; Transcortin

  • Target Background

    This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.

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