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Recombinant Human Cyclic nucleotide-gated cation channel alpha-4 (CNGA4), Truncated

ACP05996

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Specifications

Cat.No	ACP05996	Target Name	CNGA4
Target Synonyms	CNGA4; Cyclic nucleotide-gated cation channel alpha-4; Cyclic nucleotide-gated channel alpha-4; CNG channel alpha-4; CNG-4; CNG4	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IV77

Background Information

Uniprot Id

Q8IV77
Target Species

Human
Target Name

CNGA4
Target Full Name

Cyclic nucleotide-gated channel alpha-4
Target Function

Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

Cyclic nucleotide-gated cation channel (TC 1.A.1.5) family, CNGA4 subfamily
Target Synonyms

CNGA4; Cyclic nucleotide-gated cation channel alpha-4; Cyclic nucleotide-gated channel alpha-4; CNG channel alpha-4; CNG-4; CNG4
Target Background

CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signals (Munger et al., 2001 [PubMed 11739959]).

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Recombinant Human Cyclic nucleotide-gated cation channel alpha-4 (CNGA4), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Cyclic nucleotide-gated cation channel alpha-4 (CNGA4), Truncated Now

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