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| Cat.No | ACP13437 | Target Name | CCNL2 |
|---|---|---|---|
| Target Synonyms | CCNL2; SB138Cyclin-L2; Paneth cell-enhanced expression protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-520 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96S94 |
|---|
Uniprot Id
Q96S94
Target Species
Human
Target Name
CCNL2
Target Full Name
Cyclin-L2
Target Function
Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors.
Target Subcellular Location
Nucleus speckle. Nucleus, nucleoplasm.
Target Protein Families
Cyclin family, Cyclin L subfamily
Target Tissue Specificity
Widely expressed.
Target Synonyms
CCNL2; SB138Cyclin-L2; Paneth cell-enhanced expression protein
Target Background
The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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