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| Cat.No | ACP19309 | Target Name | CRIPAK |
|---|---|---|---|
| Target Synonyms | CRIPAKCysteine-rich PAK1 inhibitor; CRIPak | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-446 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N1N5 |
|---|
Uniprot Id
Q8N1N5
Target Species
Human
Target Name
CRIPAK
Target Function
Putative negative regulator of PAK1. It has been suggested that the lost of CRIPAK in breast tumors might contribute to hormonal independence.
Target Subcellular Location
Cytoplasm. Membrane. Nucleus. Note=Translocated to the nuclear compartment upon hormonal treatment by estrogen.
Target Tissue Specificity
Widely expressed with a highest expression observed in trachea, prostate and adrenal glands. Expressed in many cancer cell lines including breast cancer cells.
Target Synonyms
CRIPAKCysteine-rich PAK1 inhibitor; CRIPak
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