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Recombinant Human Cysteine–tRNA ligase, cytoplasmic (CARS1)

ACP23016

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Specifications

Cat.No	ACP23016	Target Name	CARS1
Target Synonyms	Cysteine tRNA ligase; Cars; CysRS; Cysteine--tRNA ligase; Cysteinyl tRNA synthetase, cytoplasmic; Cysteinyl-tRNA synthetase; cytoplasmic; MGC:11246; SYCC_HUMAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	2-748
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P49589

Background Information

Uniprot Id

P49589
Target Species

Human
Target Name

CARS1
Target Full Name

Cysteine--tRNA ligase, cytoplasmic
Target Function

Catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).
Target Involvement

A chromosomal aberration involving CARS is associated with inflammatory myofibroblastic tumors (IMTs). Translocation t(2;11)(p23;p15) with ALK.
Target Subcellular Location

Cytoplasm.
Target Protein Families

Class-I aminoacyl-tRNA synthetase family
Target Synonyms

Cysteine tRNA ligase; Cars; CysRS; Cysteine--tRNA ligase; Cysteinyl tRNA synthetase, cytoplasmic; Cysteinyl-tRNA synthetase; cytoplasmic; MGC:11246; SYCC_HUMAN
Target Background

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.

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Recombinant Human Cysteine–tRNA ligase, cytoplasmic (CARS1)

Specifications

Immunogen Information

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