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| Cat.No | ACP24427 | Target Name | PLA2G4B |
|---|---|---|---|
| Target Synonyms | PLA2G4B; Cytosolic phospholipase A2 beta; cPLA2-beta; EC 3.1.1.4; Phospholipase A2 group IVB | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-781 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P0C869 |
|---|
Uniprot Id
P0C869
Target Species
Human
Target Name
PLA2G4B
Target Full Name
Cytosolic phospholipase A2 beta
Target Function
Calcium-dependent phospholipase A1 and A2 and lysophospholipase that may play a role in membrane phospholipid remodeling.; Calcium-dependent phospholipase A2 and lysophospholipase. Cleaves the ester bond of the fatty acyl group attached to the sn-2 position of phosphatidylethanolamines, producing lysophospholipids that may be used in deacylation-reacylation cycles. Hydrolyzes lysophosphatidylcholines with low efficiency but is inefficient toward phosphatidylcholines.; Calcium-dependent phospholipase A1 and A2 and lysophospholipase. Cleaves the ester bond of the fatty acyl group attached to the sn-1 or sn-2 position of diacyl phospholipids (phospholipase A1 and A2 activity, respectively), producing lysophospholipids that may be used in deacylation-reacylation cycles. Can further hydrolyze lysophospholipids enabling complete deacylation. Has no activity toward alkylacyl phospholipids.
Target Subcellular Location
[Isoform 3]: Cytoplasm, cytosol. Mitochondrion membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein.; [Isoform 5]: Cytoplasm, cytosol.
Target Tissue Specificity
Widely expressed. Expressed at higher level in brain, heart, liver, cerebellum and pancreas.
Target Synonyms
PLA2G4B; Cytosolic phospholipase A2 beta; cPLA2-beta; EC 3.1.1.4; Phospholipase A2 group IVB
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