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| Cat.No | ACP24531 | Target Name | BDH1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 47-343 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q02338 |
|---|
Uniprot Id
Q02338
Target Species
Human
Target Name
BDH1
Target Full Name
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
Target Subcellular Location
Mitochondrion inner membrane. Mitochondrion matrix.
Target Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Target Research Area
Cancer
Target Synonyms
3 hydroxybutyrate dehydrogenase (heart; mitochondrial); 3-hydroxybutyrate dehydrogenase; BDH; BDH_HUMAN; BDH1; D beta hydroxybutyrate dehydrogenase; mitochondrial; D-beta-hydroxybutyrate dehydrogenase; mitochondrial
Target Background
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.
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