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| Cat.No | ACP00255 | Target Name | DND1 |
|---|---|---|---|
| Target Synonyms | RNA-binding motif, single-stranded-interacting protein 4 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-353aa |
| Mol Weight | 39.8 kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IYX4 |
|---|
Uniprot Id
Q8IYX4
Target Species
Human
Target Name
DND1
Target Full Name
Dead end protein homolog 1
Target Function
RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells. Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival. However, does not seem to be essential for PGC migration.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Research Area
Cancer
Target Synonyms
Dead end homolog 1 (zebrafish); dead end homolog 1; Dead end protein; Dead end protein homolog 1; Dead end; zebrafish; homolog; 1; DND microRNA-mediated repression inhibitor 1; dnd1; DND1_HUMAN; MGC34750; RBMS4; RNA binding motif single stranded interacting protein 4; RNA-binding motif; single-stranded-interacting protein 4; Ter
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