Recombinant Human Diamine acetyltransferase 2 (SAT2)

Uniprot Id

Q96F10

Target Species

Human

Target Name

SAT2

Target Full Name

Thialysine N-epsilon-acetyltransferase

Target Function

Catalyzes the N-acetylation of the amino acid thialysine (S-(2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur. May also catalyze acetylation of polyamines, such as norspermidine, spermidine or spermine. However, ability to acetylate polyamines is weak, suggesting that it does not act as a diamine acetyltransferase in vivo.

Target Subcellular Location

Cytoplasm.

Target Protein Families

Acetyltransferase family

Target Tissue Specificity

Widely expressed. Under physiological conditions, SSAT2 is expressed at lower level that SSAT1 (SSAT). Many tissues express only SSAT1, several tissues express both SSAT1 and SSAT2, and bone, cervix, ovary and pineal gland expressed only SSAT2.

Target Synonyms

Amino acid transporter A2; ATA2; Diamine acetyltransferase 2; Diamine N acetyltransferase 2; Polyamine N acetyltransferase; Polyamine N-acetyltransferase 2; Protein 40 9 1; SAT2; SAT2_HUMAN; SNAT2; Solute carrier family 38 member 2; Spermidine/spermine N(1)-acetyltransferase 2; Spermidine/spermine N1 acetyltransferase 2; Spermidine/spermine N1 acetyltransferase family member 2; SSAT2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2; Thialysine N-epsilon-acetyltransferase

Target Background

Enables diamine N-acetyltransferase activity and identical protein binding activity. Involved in polyamine metabolic process. Located in extracellular exosome.