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| Cat.No | ACP20741 | Target Name | DNAJC13 |
|---|---|---|---|
| Target Synonyms | DNAJC13; KIAA0678; RME8; DnaJ homolog subfamily C member 13; Required for receptor-mediated endocytosis 8; RME-8 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75165 |
|---|
Uniprot Id
O75165
Target Species
Human
Target Name
DNAJC13
Target Full Name
DnaJ homolog subfamily C member 13
Target Function
Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR. Involved in the regulation of endosomal membrane tubulation and regulates th dynamics of SNX1 on the endosomal membrane; via association with WASHC2 may link the WASH complex to the retromer SNX-BAR subcomplex.
Target Involvement
Parkinson disease (PARK)
Target Subcellular Location
Early endosome. Early endosome membrane; Peripheral membrane protein. Endosome membrane.
Target Synonyms
DNAJC13; KIAA0678; RME8; DnaJ homolog subfamily C member 13; Required for receptor-mediated endocytosis 8; RME-8
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