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Recombinant Human Dolichyl-diphosphooligosaccharide–protein glycosyltransferase subunit 4 (OST4), Truncated

ACP20305

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP20305 Target NameOST4
Target SynonymsOST4; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP0C6T2
Background Information
  • Uniprot Id

    P0C6T2

  • Target Species

    Human

  • Target Name

    OST4

  • Target Full Name

    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

  • Target Function

    Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Specifically involved in maintaining stability of STT3A-containing OST complexes

  • Target Subcellular Location

    Endoplasmic reticulum. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Note=The single transmembrane helix has a kink in the middle of the transmembrane span.

  • Target Protein Families

    OST4 family

  • Target Synonyms

    OST4; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

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