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| Cat.No | ACP14701 | Target Name | DPH3 |
|---|---|---|---|
| Target Synonyms | DPH3; DESR1; ZCSL2DPH3 homolog; CSL-type zinc finger-containing protein 2; DelGEF-interacting protein 1; DelGIP1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-82 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96FX2 |
|---|
Uniprot Id
Q96FX2
Target Species
Human
Target Name
DPH3
Target Full Name
Diphthamide biosynthesis protein 3
Target Function
Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).; Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
DPH3 family
Target Tissue Specificity
Widely expressed with highest levels in small intestine, spleen, thymus, heart, liver and lung.
Target Synonyms
DPH3; DESR1; ZCSL2DPH3 homolog; CSL-type zinc finger-containing protein 2; DelGEF-interacting protein 1; DelGIP1
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