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| Cat.No | ACP16831 | Target Name | HECTD3 |
|---|---|---|---|
| Target Synonyms | E3 ubiquitin-protein ligase HECTD3; HECD3_HUMAN; HECT; HECT domain containing protein 3; HECT domain-containing protein 3; HECTD3; Probable E3 ubiquitin protein ligase HECTD3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5T447 |
|---|
Uniprot Id
Q5T447
Target Species
Human
Target Name
HECTD3
Target Full Name
E3 ubiquitin-protein ligase HECTD3
Target Function
E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8.
Target Subcellular Location
Cytoplasm, perinuclear region.
Target Synonyms
E3 ubiquitin-protein ligase HECTD3; HECD3_HUMAN; HECT; HECT domain containing protein 3; HECT domain-containing protein 3; HECTD3; Probable E3 ubiquitin protein ligase HECTD3
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