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Recombinant Human E3 ubiquitin-protein ligase ZNF645 (ZNF645)

ACP14286

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14286 Target NameZNF645
Target SynonymsCBLL2; ZNF645E3 ubiquitin-protein ligase CBLL2; EC 2.3.2.27; Cbl proto-oncogene-like protein 2; RING-type E3 ubiquitin transferase ZNF645; Zinc finger protein 645; c-Cbl-like protein 2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-425
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N7E2
Background Information
  • Uniprot Id

    Q8N7E2

  • Target Species

    Human

  • Target Name

    CBLL2

  • Target Full Name

    E3 ubiquitin-protein ligase CBLL2

  • Target Function

    E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates.

  • Target Subcellular Location

    Cytoplasm.

  • Target Tissue Specificity

    Exclusively expressed in testis and sperm, including spermatocytes, round and elongated spermatids, and Leydig cells.

  • Target Synonyms

    CBLL2; ZNF645E3 ubiquitin-protein ligase CBLL2; EC 2.3.2.27; Cbl proto-oncogene-like protein 2; RING-type E3 ubiquitin transferase ZNF645; Zinc finger protein 645; c-Cbl-like protein 2

  • Target Background

    This gene encodes a member of the zinc finger domain-containing protein family. This family member contains both a RING-type and a C2H2-type of zinc finger domain, and it may function as an E3 ubiquitin-protein ligase. Protein localization suggests a role in human sperm production and quality control.

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