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| Cat.No | ACP09112 | Target Name | ETFDH |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 34-617 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q16134 |
|---|
Uniprot Id
Q16134
Target Species
Human
Target Name
ETFDH
Target Full Name
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
Target Function
Accepts electrons from ETF and reduces ubiquinone.
Target Involvement
Glutaric aciduria 2C (GA2C)
Target Subcellular Location
Mitochondrion inner membrane.
Target Protein Families
ETF-QO/FixC family
Target Research Area
Metabolism
Target Synonyms
Electron transfer flavoprotein ubiquinone oxidoreductase; Electron transfer flavoprotein-ubiquinone oxidoreductase; electron transferring flavoprotein dehydrogenase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; ETF QO; ETF ubiquinone oxidoreductase; ETF-QO; ETF-ubiquinone oxidoreductase; ETFD_HUMAN; Etfdh; MADD; mitochondrial
Target Background
This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed.
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