Recombinant Human Elongator complex protein 2 (ELP2), Truncated

Uniprot Id

Q6IA86

Target Species

Human

Target Name

ELP2

Target Full Name

Elongator complex protein 2

Target Function

Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

Target Involvement

Mental retardation, autosomal recessive 58 (MRT58)

Target Subcellular Location

Cytoplasm. Nucleus.

Target Protein Families

WD repeat ELP2 family

Target Synonyms

AU023723 ; Elongation protein 2 homolog (S. cerevisiae); Elongator acetyltransferase complex subunit 2; Elongator complex protein 2; elongator protein 2; ELP2; ELP2_HUMAN; Epl2; FLJ10879 ; SHINC 2; SHINC-2; SHINC2; signal transducer and activator of transcription 3 interacting protein 1; signal transducer and activator of transcription interacting protein 1; STAT3 interacting protein 1; Stat3 interacting protein; STAT3-interacting protein 1; STATIP 1; STATIP1; STATIP1 protein ; StIP; StIP1

Target Background

The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin.