Recombinant Human Embigin (EMB), Truncated

Uniprot Id

Q6PCB8

Target Species

Human

Target Name

EMB

Target Full Name

Embigin

Target Function

Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.

Target Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.

Target Synonyms

Emb; EMB_HUMAN; Embigin; Embigin homolog (mouse); embigin homolog; MGC71745; OTTHUMP00000161812; OTTHUMP00000221477; OTTHUMP00000221478; OTTHUMP00000221479

Target Background

This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1.