Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP01213 | Target Name | EPX |
|---|---|---|---|
| Target Synonyms | (EPO) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 140-715aa |
| Mol Weight | 72.1 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P11678 |
|---|
Uniprot Id
P11678
Target Species
Human
Target Name
EPX
Target Full Name
Eosinophil peroxidase
Target Function
Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.
Target Involvement
Eosinophil peroxidase deficiency (EPXD)
Target Subcellular Location
Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils.
Target Protein Families
Peroxidase family, XPO subfamily
Target Research Area
Cancer
Target Synonyms
Eosinophil peroxidase [Precursor]; Eosinophil peroxidase; Eosinophil peroxidase heavy chain; EPER; EPO; EPP; EPX; EPX PEN; PERE; PERE_HUMAN
Target Background
This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
