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| Cat.No | ACP08779 | Target Name | EIF4A2 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-407aa | Mol Weight | 73.4kDa |
| Protein Length | Full length | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14240 |
|---|
Uniprot Id
Q14240
Target Species
Human
Target Name
EIF4A2
Target Full Name
Eukaryotic initiation factor 4A-II
Target Function
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Target Protein Families
DEAD box helicase family, eIF4A subfamily
Target Research Area
Immunology
Target Synonyms
ATP dependent RNA helicase eIF4A 2; ATP-dependent RNA helicase eIF4A-2; BM-010; DDX2B; eIF 4A II; eIF-4A-II; EIF4A; eIF4A II; eIF4A-II; EIF4A2; EIF4F; Eukaryotic initiation factor 4A II; Eukaryotic initiation factor 4A-II; eukaryotic translation initiation factor 4A isoform 2; Eukaryotic translation initiation factor 4A2; IF4A2_HUMAN; N-terminally processed
Target Background
Enables ATP hydrolysis activity. Involved in negative regulation of RNA-directed 5'-3' RNA polymerase activity. Located in perinuclear region of cytoplasm.
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