Recombinant Human Exocyst complex component 4 (EXOC4), Truncated

Uniprot Id

Q96A65

Target Species

Human

Target Name

EXOC4

Target Full Name

Exocyst complex component 4

Target Function

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

Target Subcellular Location

Midbody, Midbody ring. Cell projection.

Target Protein Families

SEC8 family

Target Synonyms

dSec8; EXOC 4; Exoc4; EXOC4_HUMAN; Exocyst complex component 4; Exocyst complex component SEC8; KIAA1699; MGC27170; REC 8; REC8; rSec 8; Sec 8; Sec 8p; Sec8; SEC8 like 1; SEC8 protein; Sec8L1; Sec8p

Target Background

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.