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| Cat.No | ACP24438 | Target Name | FBXO45 |
|---|---|---|---|
| Target Synonyms | F box protein 45; F-box only protein 45; F-box/SPRY domain-containing protein 1; FBSP1_HUMAN; FBX45; fbxo45; hFbxo45 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-286 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P0C2W1 |
|---|
Uniprot Id
P0C2W1
Target Species
Human
Target Name
FBXO45
Target Full Name
F-box/SPRY domain-containing protein 1
Target Function
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons. May control synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation.
Target Subcellular Location
Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, presynaptic cell membrane.
Target Protein Families
FBXO45/Fsn family
Target Synonyms
F box protein 45; F-box only protein 45; F-box/SPRY domain-containing protein 1; FBSP1_HUMAN; FBX45; fbxo45; hFbxo45
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