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| Cat.No | ACP09716 | Target Name | FRMD4B |
|---|---|---|---|
| Target Synonyms | 6030440G05Rik; FERM domain-containing protein 4B; FRM4B_HUMAN; Frmd4b; GRP1-binding protein GRSP1; GRSP1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y2L6 |
|---|
Uniprot Id
Q9Y2L6
Target Species
Human
Target Name
FRMD4B
Target Full Name
FERM domain-containing protein 4B
Target Function
Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell junction, tight junction. Cell junction, adherens junction.
Target Synonyms
6030440G05Rik; FERM domain-containing protein 4B; FRM4B_HUMAN; Frmd4b; GRP1-binding protein GRSP1; GRSP1
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