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| Cat.No | ACP03383 | Target Name | FGF14 |
|---|---|---|---|
| Target Synonyms | FGF14; FHF4Fibroblast growth factor 14; FGF-14; Fibroblast growth factor homologous factor 4; FHF-4 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-252aa |
| Mol Weight | 55.5kDa | Protein Length | Full Length of Isoform 2 |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92915 |
|---|
Uniprot Id
Q92915
Target Species
Human
Target Name
FGF14
Target Full Name
Fibroblast growth factor 14
Target Function
Probably involved in nervous system development and function.
Target Involvement
Spinocerebellar ataxia 27 (SCA27)
Target Subcellular Location
Nucleus.
Target Protein Families
Heparin-binding growth factors family
Target Tissue Specificity
Nervous system.
Target Research Area
Signal Transduction
Target Synonyms
FGF14; FHF4Fibroblast growth factor 14; FGF-14; Fibroblast growth factor homologous factor 4; FHF-4
Target Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.
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