Recombinant Human Fibroblast growth factor 6 (FGF6)

Uniprot Id

P10767

Target Species

Human

Target Name

FGF6

Target Full Name

Fibroblast growth factor 6

Target Function

Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.

Target Subcellular Location

Secreted, extracellular space.

Target Protein Families

Heparin-binding growth factors family

Target Tissue Specificity

Leukemia cell lines with platelet/ megakaryocytic differentiation potential.

Target Synonyms

FGF 6; FGF-6; Fgf6; FGF6_HUMAN; Fibroblast growth factor 6; Fibroblast growth factor 6 precursor; HBGF 6; HBGF-6; HBGF6; Heparin secretory-transforming protein 2; Heparin-binding growth factor 6; HST 2 ; HST-2; HST2 ; HSTF-2

Target Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.