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Recombinant Human Filamin A-interacting protein 1-like (FILIP1L), Truncated

ACP17400

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17400 Target NameFILIP1L
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ4L180
Background Information
  • Uniprot Id

    Q4L180

  • Target Species

    Human

  • Target Name

    FILIP1L

  • Target Full Name

    Filamin A-interacting protein 1-like

  • Target Function

    Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.

  • Target Subcellular Location

    Cytoplasm. Membrane. Nucleus.

  • Target Protein Families

    FILIP1 family

  • Target Tissue Specificity

    Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. D

  • Target Research Area

    Cancer

  • Target Synonyms

    130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; COL4A3BPIP; DOC-1; DOC1; Downregulated in ovarian cancer 1 81 kDa isoform; FIL1L_HUMAN; Filamin A-interacting protein 1-like; FILIP1L; GIP130; GIP130a; GIP130b; GIP130c; GIP90; GPBP interacting protein 90; Protein down-regulated in ovarian cancer 1

  • Target Background

    Predicted to be located in cytoplasm; membrane; and nucleus.

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