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Recombinant Human Formin-binding protein 1-like (FNBP1L)

ACP16892

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16892 Target NameFNBP1L
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-605Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ5T0N5
Background Information
  • Uniprot Id

    Q5T0N5

  • Target Species

    Human

  • Target Name

    FNBP1L

  • Target Full Name

    Formin-binding protein 1-like

  • Target Function

    Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Protein Families

    FNBP1 family

  • Target Synonyms

    C1orf39; FBP1L_HUMAN; FNBP 1L; fnbp1l; Formin binding protein 1 like; Formin-binding protein 1-like; TOCA 1; Toca-1; TOCA1; Transducer of Cdc42 dependent actin assembly 1; Transducer of Cdc42 dependent actin assembly protein 1; Transducer of Cdc42-dependent actin assembly protein 1

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