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Recombinant Human FYVE, RhoGEF and PH domain-containing protein 1 (FGD1), Truncated

ACP24559

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP24559 Target NameFGD1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP98174
Background Information
  • Uniprot Id

    P98174

  • Target Species

    Human

  • Target Name

    FGD1

  • Target Full Name

    FYVE, RhoGEF and PH domain-containing protein 1

  • Target Function

    Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.

  • Target Involvement

    Aarskog-Scott syndrome (AAS)

  • Target Subcellular Location

    Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton.

  • Target Tissue Specificity

    Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.

  • Target Synonyms

    AAS; Faciogenital dysplasia 1 protein; FGD1; FGD1_HUMAN; FGDY; FYVE RhoGEF and PH domain containing protein 1; FYVE; RhoGEF and PH domain-containing protein 1; Rho/Rac GEF; Rho/Rac guanine nucleotide exchange factor FGD1; ZFYVE3; Zinc finger FYVE domain containing protein 3; Zinc finger FYVE domain-containing protein 3

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