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| Cat.No | ACP14829 | Target Name | GAS2L2 |
|---|---|---|---|
| Target Synonyms | GAS2L2; GAR17; GAS2-like protein 2; GAS2-related protein on chromosome 17; Growth arrest-specific protein 2-like 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NHY3 |
|---|
Uniprot Id
Q8NHY3
Target Species
Human
Target Name
GAS2L2
Target Full Name
GAS2-like protein 2
Target Function
Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers. Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell membrane. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cytoskeleton, cilium basal body.
Target Protein Families
GAS2 family
Target Tissue Specificity
Expressed in bronchial and nasal epithelial cells (at protein level). Expressed in brain, kidney, lung, testis, fallopian tubes, and skeletal muscle. Expressed at low levels in stomach and colon.
Target Synonyms
GAS2L2; GAR17; GAS2-like protein 2; GAS2-related protein on chromosome 17; Growth arrest-specific protein 2-like 2
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