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Recombinant Human Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2)

ACP23405

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23405 Target NameGPD2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range43-727Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP43304
Background Information
  • Uniprot Id

    P43304

  • Target Species

    Human

  • Target Name

    GPD2

  • Target Full Name

    Glycerol-3-phosphate dehydrogenase, mitochondrial

  • Target Function

    Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    FAD-dependent glycerol-3-phosphate dehydrogenase family

  • Target Research Area

    Others

  • Target Synonyms

    GDH2; Glycerol 3 phosphate dehydrogenase 2 (mitochondrial); Glycerol 3 phosphate dehydrogenase 2; Glycerol 3 phosphate dehydrogenase mitochondrial; Glycerol-3-phosphate dehydrogenase; GPD 2; GPD M; GPD-M; gpd2; GPDH M; GPDH-M; GPDM; GPDM_HUMAN; mGPDH; mitochondrial; Mitochondrial glycerophosphate dehydrogenase; mtGPD; OTTHUMP00000162788; OTTHUMP00000204452; OTTHUMP00000204453; OTTHUMP00000204458

  • Target Background

    The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.

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