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| Cat.No | ACP17290 | Target Name | Gripap1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q4V328 |
|---|
Uniprot Id
Q4V328
Target Species
Human
Target Name
GRIPAP1
Target Full Name
GRIP1-associated protein 1
Target Function
Regulates the endosomal recycling back to the neuronal plasma membrane, possibly by connecting early and late recycling endosomal domains and promoting segregation of recycling endosomes from early endosomal membranes. Involved in the localization of recycling endosomes to dendritic spines, thereby playing a role in the maintenance of dendritic spine morphology. Required for the activity-induced AMPA receptor recycling to dendrite membranes and for long-term potentiation and synaptic plasticity.; Functions as a scaffold protein to facilitate MAP3K1/MEKK1-mediated activation of the JNK1 kinase by phosphorylation, possibly by bringing MAP3K1/MEKK1 and JNK1 in close proximity.
Target Subcellular Location
Early endosome membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse.
Target Synonyms
DKFZp434P0630; DXImx47e; GRAP1_HUMAN; GRASP 1; GRASP-1; GRASP1; GRIP 1 associated protein 1; GRIP associated protein 1 ; GRIP1 associated protein 1; GRIP1-associated protein 1; GRIPAP 1; GRIPAP1; KIAA1167; MGC126593; MGC126595; MPMGp800B12492Q3; Sfc10; TAMALIN
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