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| Cat.No | ACP11872 | Target Name | PLA2G2F |
|---|---|---|---|
| Target Synonyms | PLA2G2FGroup IIF secretory phospholipase A2; GIIF sPLA2; sPLA2-IIF; EC 3.1.1.4; Phosphatidylcholine 2-acylhydrolase 2F | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 21-168 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BZM2 |
|---|
Uniprot Id
Q9BZM2
Target Species
Human
Target Name
PLA2G2F
Target Full Name
Group IIF secretory phospholipase A2
Target Function
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at the sn-2 position of phospholipids (phospholipase A2 activity), the catalytic efficiency decreasing in the following order: phosphatidylglycerols > phosphatidylethanolamines > phosphatidylcholines > phosphatidylserines. May play a role in lipid mediator production in inflammatory conditions, by providing arachidonic acid to downstream cyclooxygenases and lipoxygenases.
Target Subcellular Location
[Isoform 1]: Secreted. Cell membrane; Peripheral membrane protein.
Target Protein Families
Phospholipase A2 family
Target Tissue Specificity
Expressed at high levels in placenta, testis, thymus and at lower levels in heart, kidney, liver and prostate. Highly expressed in rheumatoid arthritic tissues, including synovial lining cells in the intima, capillary endothelial cells and plasma cells.
Target Synonyms
PLA2G2FGroup IIF secretory phospholipase A2; GIIF sPLA2; sPLA2-IIF; EC 3.1.1.4; Phosphatidylcholine 2-acylhydrolase 2F
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