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| Cat.No | ACP00137 | Target Name | GDF2 |
|---|---|---|---|
| Target Synonyms | GDF-2;Bone morphogenetic protein 9;BMP-9 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 300-429aa |
| Mol Weight | 22.8 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UK05 |
|---|
Uniprot Id
Q9UK05
Target Species
Human
Target Name
GDF2
Target Full Name
Growth/differentiation factor 2
Target Function
Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
Target Involvement
Telangiectasia, hereditary hemorrhagic, 5 (HHT5)
Target Subcellular Location
Secreted.
Target Protein Families
TGF-beta family
Target Tissue Specificity
Detected in blood plasma (at protein level).
Target Research Area
Cell Biology
Target Synonyms
GDF2; BMP9Growth/differentiation factor 2; GDF-2; Bone morphogenetic protein 9; BMP-9
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