Recombinant Human Guanylate cyclase soluble subunit alpha-3 (GUCY1A3)

Uniprot Id

Q02108

Target Species

Human

Target Name

GUCY1A1

Target Full Name

Guanylate cyclase soluble subunit alpha-1

Target Involvement

Moyamoya disease 6 with achalasia (MYMY6)

Target Subcellular Location

Cytoplasm.

Target Protein Families

Adenylyl cyclase class-4/guanylyl cyclase family

Target Tissue Specificity

Detected in brain cortex and lung (at protein level).

Target Synonyms

GC S alpha 1; GC SA3; GCS alpha 1; GCS alpha 3; GCS-alpha-1; GCS-alpha-3; GCYA3_HUMAN; Guanylate cyclase 1 soluble alpha 3; Guanylate cyclase soluble subunit alpha 1; Guanylate cyclase soluble subunit alpha 3; Guanylate cyclase soluble subunit alpha-3; Guanylate cyclase; nitric oxide-sensitive; alpha-1 subunit; Guc1a1; GUC1A3; GUCA3; GUCSA3; Gucy1a1; Gucy1a3; MYMY6; nitric oxide-sensitive Guanylate cyclase; alpha-1 subunit; NOGC; alpha-1 subunit; Soluble guanylate cyclase large subunit

Target Background

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3', 5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.