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Recombinant Human Haptoglobin-related protein (HPR)

ACP20051

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP20051 Target NameHPR
Target SynonymsA-259H10.2; Haptoglobin related locus; haptoglobin related protein; Haptoglobin-related protein; HP; hpr; HPTR_HUMANFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range20-348
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP00739
Background Information
  • Uniprot Id

    P00739

  • Target Species

    Human

  • Target Name

    HPR

  • Target Full Name

    Haptoglobin-related protein

  • Target Function

    Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Peptidase S1 family

  • Target Tissue Specificity

    In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in Hep-G2 and leukemia MOLT-4 cell

  • Target Synonyms

    A-259H10.2; Haptoglobin related locus; haptoglobin related protein; Haptoglobin-related protein; HP; hpr; HPTR_HUMAN

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