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| Cat.No | ACP00245 | Target Name | HEBP1 |
|---|---|---|---|
| Target Synonyms | p22HBP | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-189aa |
| Mol Weight | 48.6 kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NRV9 |
|---|
Uniprot Id
Q9NRV9
Target Species
Human
Target Name
HEBP1
Target Full Name
Heme-binding protein 1
Target Function
May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.
Target Subcellular Location
Cytoplasm.
Target Protein Families
HEBP family
Target Research Area
Cardiovascular
Target Synonyms
HBP; HEBP; Hebp1; HEBP1_HUMAN; Heme binding protein 1; Heme-binding protein 1; p22HBP
Target Background
The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells.
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