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| Cat.No | ACP00318 | Target Name | H2AC18 |
|---|---|---|---|
| Target Synonyms | H2A-clustered histone 18;H2A-clustered histone 19;Histone H2A.2 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 2-130aa |
| Mol Weight | 20.9 | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 95% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6FI13 |
|---|
Uniprot Id
Q6FI13
Target Species
Human
Target Name
H2AC18
Target Full Name
Histone H2A type 2-A
Target Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Histone H2A family
Target Research Area
Cancer
Target Synonyms
H2A histone family; member O; H2A2A_HUMAN; H2aa3; H2aa4; H2AFO; HIST2H2AA; HIST2H2AA3; HIST2H2AA4; histone 2; histone cluster 2; H2aa3 ; Histone H2A type 2-A; Histone H2A.2; Histone H2A/o; histone H2A/r; H2AC18; H2AC19
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