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Recombinant Human Homeobox protein CDX-1 (CDX1)

ACP23121

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Specifications

Cat.No	ACP23121	Target Name	CDX1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-265	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P47902

Background Information

Uniprot Id

P47902
Target Species

Human
Target Name

CDX1
Target Full Name

Homeobox protein CDX-1
Target Function

Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Target Subcellular Location

Nucleus.
Target Protein Families

Caudal homeobox family
Target Tissue Specificity

Intestinal epithelium.
Target Synonyms

Caudal type homeo box transcription factor 1 ; Caudal type homeobox 1; Caudal type homeobox protein ; Caudal type homeobox protein CDX1; Caudal type homeobox transcription factor 1; Caudal-type homeobox protein 1; CDX1; CDX1_HUMAN; Homeobox protein CDX 1; Homeobox protein CDX-1; MGC116915; OTTHUMP00000160524
Target Background

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.

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Recombinant Human Homeobox protein CDX-1 (CDX1)

Specifications

Immunogen Information

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