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Recombinant Human InaD-like protein (INADL), Truncated

ACP13926

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Specifications

Cat.No	ACP13926	Target Name	PATJ
Target Synonyms	PATJ; CIPP; INADL; InaD-like protein; Inadl protein; hINADL; Channel-interacting PDZ domain-containing protein; Pals1-associated tight junction protein; Protein associated to tight junctions	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8NI35

Background Information

Uniprot Id

Q8NI35
Target Species

Human
Target Name

PATJ
Target Full Name

InaD-like protein
Target Function

Scaffolding protein that facilitates the localization of proteins to the cell membrane. Required for the correct formation of tight junctions and epithelial apico-basal polarity. Positively regulates epithelial cell microtubule elongation and cell migration, possibly via facilitating localization of PRKCI/aPKC and PAR3D/PAR3 at the leading edge of migrating cells. Plays a role in the correct reorientation of the microtubule-organizing center during epithelial migration. May regulate the surface expression and/or function of ASIC3 in sensory neurons. May recruit ARHGEF18 to apical cell-cell boundaries
Target Subcellular Location

Cell junction, tight junction. Apical cell membrane; Peripheral membrane protein. Cytoplasm, perinuclear region.
Target Tissue Specificity

Expressed in renal tubules (at protein level). Expressed in bladder, testis, ovary, small intestine, colon, heart, skeletal muscle, pancreas and cerebellum in the brain.
Target Synonyms

PATJ; CIPP; INADL; InaD-like protein; Inadl protein; hINADL; Channel-interacting PDZ domain-containing protein; Pals1-associated tight junction protein; Protein associated to tight junctions

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Recombinant Human InaD-like protein (INADL), Truncated

Specifications

Immunogen Information

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